Prospects for the development of new herbicides based on natural compounds

Growing most major crops currently involves the use of chemical herbicides to control weeds. However, their regular can lead such undesirable consequences as contamination soil and groundwater, accumulation residues in crop, emergence resistant populations Therefore, developing eco-friendly with new mechanisms action is necessary. Natural phytotoxins plant or microbial origin serve prototypes for active ingredients herbicides. This review considers: 1) main modern trends development herbicides; 2) practical achievements natural compounds weed control; 3) basic components synthetic Analysis existing literature allowed us identify some important approaches nature-derived herbicides: combination virtual screening libraries high-throughput selected substances vitro vivo; computer modelling optimization molecules using physico-chemical predictors molecular docking; adjuvants formulations, particular on nanoscale, reduce application rates risks environment. The these likely discovery promising herbicidal both organic conventional agriculture.